Notre plateforme peut héberger des expériences très diverses mettant en œuvre des radio-isotopes : études métaboliques, binding, radiochimie, dosage RIA, post-marquage protéique, post-marquage acide nucléique, autoradiographie… Les projets sont réalisés avec différentes équipes de chimistes, biologistes, écophysiologistes…
Babin, V.; Tournier, B. B.; Davis, A.; Dubost, E.; Pigrée, G.; Lohier, J.; Reboul, V.; Cailly, T.; Bouillon, J.; Millet, P.; et al. Design of Iodinated Radioligands for SPECT Imaging of Central Human 5-HT4R Using a Ligand Lipophilicity Efficiency Approach. Bioorg. Chem. 2020, 96 (December 2019), 103582.
PMID: 31978687
Grand, M., Aubourg, M., Pikis, A., Thompson, J., Deutscher, J., Hartke, A., et Sauvageot, N. (2019). Characterization of the gen locus involved in β-1,6-oligosaccharide utilization by Enterococcus faecalis. Mol. Microbiol.
PMID: 31529727
Dubost, E.; Babin, V.; Benoist, F.; Hébert, A.; Pigrée, G.; Bouillon, J.-P.; Fabis, F.; Cailly, T. Improvements of C–H Radio-Iodination of N-Acylsulfonamides toward Implementation in Clinics. Synthesis 2019, 51 (23), 4393–4400.
Grand, M., Blancato, V.S., Espariz, M., Deutscher, J., Pikis, A., Hartke, A., Magni, C., et Sauvageot, N. (2019) Enterococcus faecalis MalR acts as a repressor of the maltose operons and additionally mediates their catabolite repression via direct interaction with seryl-phosphorylated-HPr. Mol Microbiol. doi: 10.1111/mmi.14431.
PMID: 31755602
Pigree Gilbert; Cruet-Hennequart Severine; Barbey Pierre; Cesini Johann; Marcelli Christian; Peyronnet Damien; Vigne Jonathan; Agostini Denis Transfer of yttrium-90 to breast milk during radiosynoviorthesis of the knee joint, European journal of nuclear medicine and molecular imaging (2019), 46(8), 1591-1593.
PMID: 31069455
James M, Masclaux-Daubresse C, Marmagne A, Azzopardi M, Laîné P, Goux D, Etienne P, Trouverie J (2019) A new role for SAG12 cysteine protease in roots of Arabidopsis thaliana. Frontiers in Plant Science.
PMID: 30687379
James M, Poret M, Masclaux-Daubresse C, Marmagne A, Coquet L, Jouenne T, Chan P, Trouverie J, Etienne P (2018) SAG12, a major cysteine protease involved in nitrogen allocation during senescence for seed production in Arabidopsis thaliana. Plant & Cell Physiology 59:2052-2063.
PMID: 29982633
Dubost, E.; Babin, V.; Benoist, F.; Hébert, A.; Barbey, P.; Chollet, C.; Bouillon, J.-P.; Manrique, A.; Pieters, G.; Fabis, F.; et al. Palladium-Mediated Site-Selective C–H Radio-Iodination. Org. Lett. 2018, 20 (19), 6302–6305.
PMID: 30232893
Joyet, P., Mokhtari, A., Riboulet-Bisson, E., Blancato, V.S., Espariz, M., Magni, C., Hartke, A., Deutscher, J., et Sauvageot, N. (2017). Enzymes Required for Maltodextrin Catabolism in Enterococcus faecalis Exhibit Novel Activities. Appl. Environ. Microbiol. 83.
PMID: 28455338
Sauvageot, N., Mokhtari, A., Joyet, P., Budin-Verneuil, A., Blancato, V.S., Repizo, G.D., Henry, C., Pikis, A., Thompson, J., Magni, C., et al. (2017). Enterococcus faecalis Uses a Phosphotransferase System Permease and a Host Colonization-Related ABC Transporter for Maltodextrin Uptake. J. Bacteriol. 199.
PMID: 28242718
Louessard, M., Bardou, I., Lemarchand, E., Thiebaut, A. M., Parcq, J., Leprince, J., Roussel, B. D. (2017). Activation of cell surface GRP78 decreases endoplasmic reticulum stress and neuronal death. Cell death and differentiation, 24(9), 1518–1529.
PMID: 28644439
DNA adducts in marine fish as biological marker of genotoxicity in environmental monitoring : The way forward. Pampanin DM, Brooks SJ, Grøsvik BE, Le Goff J, Meier S, Sydnes MO. Mar Environ Res. 2017 Apr;125:49-62. doi: 10.1016/j.marenvres.2017.01.002. Epub 2017 Jan 21. Review.
PMID: 28167386
Integrated monitoring of chemicals and their effects on four sentinel species, Limanda limanda, Platichthys flesus, Nucella lapillus and Mytilus sp., in Seine Bay: A key step towards applying biological effects to monitoring. Burgeot T, Akcha F, Ménard D, Robinson C, Loizeau V, Brach-Papa C, Martínez-Gòmez C, Le Goff J, Budzinski H, Le Menach K, Cachot J, Minier C, Broeg K, Hylland K. Mar Environ Res. 2017 Mar;124:92-105. doi: 10.1016/j.marenvres.2016.10.009. Epub 2016 Nov 2.
PMID: 27839718